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Differences in Metabolite-mediated Toxicity of Tamoxifen in Rodents vs. Humans Elucidated with DNA/microsomes Electro-optical Arrays and Nanoreactors

Tamoxifen, a therapeutic and chemopreventive breast cancer drug, was chosen as a model compound because of acknowledged species specific toxicity differences. Emerging approaches utilizing electro-optical arrays and nanoreactors based on DNA/microsomes films were used to compare metabolite-mediated...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Zhao, Linlin, Krishnan, Sadagopan, Zhang, Yun, Schenkman, John B., Rusling, James F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657835/
https://ncbi.nlm.nih.gov/pubmed/19166339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx8004295
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