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Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein

The paramyxovirus parainfluenza virus 5 (PIV5) enters cells by fusion of the viral envelope with the plasma membrane through the concerted action of the fusion (F) protein and the receptor binding protein hemagglutinin-neuraminidase. The F protein folds initially to form a trimeric metastable prefus...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Welch, Brett D., Liu, Yuanyuan, Kors, Christopher A., Leser, George P., Jardetzky, Theodore S., Lamb, Robert A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478641/
https://ncbi.nlm.nih.gov/pubmed/23012473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213802109
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