Fat-Specific DsbA-L Overexpression Promotes Adiponectin Multimerization and Protects Mice From Diet-Induced Obesity and Insulin Resistance

The antidiabetic and antiatherosclerotic effects of adiponectin make it a desirable drug target for the treatment of metabolic and cardiovascular diseases. However, the adiponectin-based drug development approach turns out to be difficult due to extremely high serum levels of this adipokine. On the...

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Main Authors: Liu, Meilian, Xiang, Ruihua, Wilk, Sarah Ann, Zhang, Ning, Sloane, Lauren B., Azarnoush, Kian, Zhou, Lijun, Chen, Hongzhi, Xiang, Guangda, Walter, Christi A., Austad, Steven N., Musi, Nicolas, DeFronzo, Ralph A., Asmis, Reto, Scherer, Philipp E., Dong, Lily Q., Liu, Feng
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2012
主題:
Obesity Studies
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478538/
https://ncbi.nlm.nih.gov/pubmed/22807031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0169
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