Fat-Specific DsbA-L Overexpression Promotes Adiponectin Multimerization and Protects Mice From Diet-Induced Obesity and Insulin Resistance

The antidiabetic and antiatherosclerotic effects of adiponectin make it a desirable drug target for the treatment of metabolic and cardiovascular diseases. However, the adiponectin-based drug development approach turns out to be difficult due to extremely high serum levels of this adipokine. On the...

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Autori principali: Liu, Meilian, Xiang, Ruihua, Wilk, Sarah Ann, Zhang, Ning, Sloane, Lauren B., Azarnoush, Kian, Zhou, Lijun, Chen, Hongzhi, Xiang, Guangda, Walter, Christi A., Austad, Steven N., Musi, Nicolas, DeFronzo, Ralph A., Asmis, Reto, Scherer, Philipp E., Dong, Lily Q., Liu, Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2012
Soggetti:
Obesity Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478538/
https://ncbi.nlm.nih.gov/pubmed/22807031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0169
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