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Fat-Specific DsbA-L Overexpression Promotes Adiponectin Multimerization and Protects Mice From Diet-Induced Obesity and Insulin Resistance

The antidiabetic and antiatherosclerotic effects of adiponectin make it a desirable drug target for the treatment of metabolic and cardiovascular diseases. However, the adiponectin-based drug development approach turns out to be difficult due to extremely high serum levels of this adipokine. On the...

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Detalhes bibliográficos
Main Authors: Liu, Meilian, Xiang, Ruihua, Wilk, Sarah Ann, Zhang, Ning, Sloane, Lauren B., Azarnoush, Kian, Zhou, Lijun, Chen, Hongzhi, Xiang, Guangda, Walter, Christi A., Austad, Steven N., Musi, Nicolas, DeFronzo, Ralph A., Asmis, Reto, Scherer, Philipp E., Dong, Lily Q., Liu, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478538/
https://ncbi.nlm.nih.gov/pubmed/22807031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0169
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