Alterations in Lipid Signaling Underlie Lipodystrophy Secondary to AGPAT2 Mutations

Congenital generalized lipodystrophy (CGL), secondary to AGPAT2 mutation is characterized by the absence of adipocytes and development of severe insulin resistance. In the current study, we investigated the adipogenic defect associated with AGPAT2 mutations. Adipogenesis was studied in muscle-derive...

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Bibliografiske detaljer
Main Authors: Subauste, Angela R., Das, Arun K., Li, Xiangquan, Elliot, Brandon, Evans, Charles, El Azzouny, Mahmoud, Treutelaar, Mary, Oral, Elif, Leff, Todd, Burant, Charles F.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2012
Fag:
Pathophysiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478532/
https://ncbi.nlm.nih.gov/pubmed/22872237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0004
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