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Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity
Triglyceride synthesis in most mammalian tissues involves the sequential addition of fatty acids to a glycerol backbone, with unique enzymes required to catalyze each acylation step. Acylation at the sn-2 position requires 1-acylglycerol-3-phosphate O-acyltransferase (AGPAT) activity. To date, seven...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901549/ https://ncbi.nlm.nih.gov/pubmed/16436371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M500553-JLR200 |
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