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The Yaa locus and IFNα fine tune germinal center B cell selection in murine SLE
Male NZW/BXSB.Yaa (W/B) mice express two copies of TLR7 and develop pathogenic autoantibodies whereas females with only one copy of TLR7 have attenuated disease. Our goal was to analyze the regulation of the autoantibody response in male and female W/B mice bearing the autoreactive site-directed hea...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478483/ https://ncbi.nlm.nih.gov/pubmed/23024275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200745 |
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