Rapamycin Activates Autophagy and Improves Myelination in Explant Cultures from Neuropathic Mice

Misexpression and cytosolic retention of peripheral myelin protein 22 (PMP22) within Schwann cells (SCs) is associated with a genetically heterogeneous group of demyelinating peripheral neuropathies. PMP22 overproducer C22 and spontaneous mutant Trembler J (TrJ) mice display neuropathic phenotypes a...

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Hauptverfasser: Rangaraju, Sunitha, Verrier, Jonathan D., Madorsky, Irina, Nicks, Jessica, Dunn, William A., Notterpek, Lucia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478092/
https://ncbi.nlm.nih.gov/pubmed/20739560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1356-10.2010
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