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Pharmacological induction of the heat shock response improves myelination in a neuropathic model

Misexpression and intracellular retention of peripheral myelin protein 22 (PMP22) is associated with hereditary neuropathies in humans, including Charcot-Marie-Tooth disease type 1A (CMT1A). Mice expressing extra copies of the human PMP22, termed C22, display morphologic and behavioral characteristi...

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Détails bibliographiques
Auteurs principaux: Rangaraju, Sunitha, Madorsky, Irina, Pileggi, Jocelyn Go, Kamal, Adeela, Notterpek, Lucia
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120161/
https://ncbi.nlm.nih.gov/pubmed/18655835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.06.015
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