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Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit

Triggered release of Ca(2+) from an individual sarcoplasmic reticulum (SR) Ca(2+) release unit (CRU) is the fundamental event of cardiac excitation–contraction coupling, and spontaneous release events (sparks) are the major contributor to diastolic Ca(2+) leak in cardiomyocytes. Previous model studi...

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מידע ביבליוגרפי
Main Authors: Hake, Johan, Edwards, Andrew G, Yu, Zeyun, Kekenes-Huskey, Peter M, Michailova, Anushka P, McCammon, J Andrew, Holst, Michael J, Hoshijima, Masahiko, McCulloch, Andrew D
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Science Inc 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477749/
https://ncbi.nlm.nih.gov/pubmed/22495592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.227926
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