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Numerical Analysis of Ca(2+) Signaling in Rat Ventricular Myocytes with Realistic Transverse-Axial Tubular Geometry and Inhibited Sarcoplasmic Reticulum

The t-tubules of mammalian ventricular myocytes are invaginations of the cell membrane that occur at each Z-line. These invaginations branch within the cell to form a complex network that allows rapid propagation of the electrical signal, and hence synchronous rise of intracellular calcium (Ca(2+))....

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Detalhes bibliográficos
Main Authors: Cheng, Yuhui, Yu, Zeyun, Hoshijima, Masahiko, Holst, Michael J., McCulloch, Andrew D., McCammon, J. Andrew, Michailova, Anushka P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965743/
https://ncbi.nlm.nih.gov/pubmed/21060856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000972
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