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Delayed fusion and altered gene expression contribute to semicircular canal defects in Chd7 deficient mice
Proper morphogenesis of inner ear semicircular canals requires precise regulation of cellular proliferation, epithelial-to-mesenchymal transition, and fusion of epithelial plates. Epigenetic regulation of these processes is not well understood, but is likely to involve chromatin remodeling enzymes....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477510/ https://ncbi.nlm.nih.gov/pubmed/22705977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2012.06.002 |
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