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Opposing phenotypes in mice with Smith-Magenis deletion and Potocki -Lupski duplication syndromes suggest gene dosage effects on fluid consumption behavior
A quantitative long-term fluid consumption and fluid licking assay was performed in two mouse models with either an ~ 2Mb genomic deletion, Df(11)17, or the reciprocal duplication CNV, Dp(11)17, analogous to the human genomic rearrangements causing either Smith-Magenis syndrome [SMS; OMIM #182290] o...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477298/ https://ncbi.nlm.nih.gov/pubmed/22991245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.35601 |
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