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Mouse Models of Genomic Syndromes as Tools for Understanding the Basis of Complex Traits: An Example with the Smith-Magenis and the Potocki-Lupski Syndromes

Each human's genome is distinguished by extra and missing DNA that can be “benign” or powerfully impact everything from development to disease. In the case of genomic disorders DNA rearrangements, such as deletions or duplications, correlate with a clinical specific phenotype. The clinical pres...

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Detalhes bibliográficos
Main Authors: Carmona-Mora, P, Molina, J, Encina, C.A, Walz, K
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709937/
https://ncbi.nlm.nih.gov/pubmed/19949547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920209788488508
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