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Mouse Models of Genomic Syndromes as Tools for Understanding the Basis of Complex Traits: An Example with the Smith-Magenis and the Potocki-Lupski Syndromes

Each human's genome is distinguished by extra and missing DNA that can be “benign” or powerfully impact everything from development to disease. In the case of genomic disorders DNA rearrangements, such as deletions or duplications, correlate with a clinical specific phenotype. The clinical pres...

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Main Authors: Carmona-Mora, P, Molina, J, Encina, C.A, Walz, K
Format: Artigo
Jezik:Inglês
Izdano: Bentham Science Publishers Ltd. 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709937/
https://ncbi.nlm.nih.gov/pubmed/19949547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920209788488508
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