The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence

The endogenous cannabinoid anandamide (AEA) exerts the majority of its effects at CB(1) and CB(2) receptors and is degraded by fatty acid amide hydrolase (FAAH). FAAH KO mice and animals treated with FAAH inhibitors are impaired in their ability to hydrolyze AEA and other non-cannabinoid lipid signa...

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Hlavní autoři: Muldoon, Pretal P., Lichtman, Aron H., Parsons, Loren H., Damaj, M. Imad
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477273/
https://ncbi.nlm.nih.gov/pubmed/22705310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.05.015
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