Immunohistochemical Testing of Conventional Adenomas for Loss of Expression of Mismatch Repair proteins in Lynch Syndrome Mutation Carriers: a Case Series from the Australasian Site of the Colon Cancer Family Registry

Debate continues as to the usefulness of assessing adenomas for loss of mismatch repair protein expression to identify individuals with suspected Lynch syndrome. We tested 109 polyps from 69 proven mutation carriers (35 females and 34 males) belonging to 49 Lynch syndrome families. All polyps were t...

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Hauptverfasser: Walsh, Michael D, Buchanan, Daniel D, Pearson, Sally-Ann, Clendenning, Mark, Jenkins, Mark A, Win, Aung Ko, Walters, Rhiannon J, Spring, Kevin, Nagler, Belinda, Pavluk, Erika, Arnold, Sven T, Goldblatt, Jack, George, Jill, Suthers, Graeme, Phillips, Kerry, Hopper, John L, Jass, Jeremy R, Baron, John A, Ahnen, Dennis, Thibodeau, Stephen, Lindor, Noralane, Parry, Susan, Walker, Neal, Rosty, Christophe, Young, Joanne P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477239/
https://ncbi.nlm.nih.gov/pubmed/22322191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2011.209
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