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P6981, An Arylstibonic Acid, Is a Novel Low Nanomolar Inhibitor of cAMP Response Element-Binding Protein Binding to DNA

Several basic leucine zipper (B-ZIP) transcription factors have been implicated in cancer, substance abuse, and other pathological conditions. We previously identified arylstibonic acids that bind to B-ZIP proteins and inhibit their interaction with DNA. In this study, we used electrophoretic mobili...

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Detalhes bibliográficos
Main Authors: Zhao, Jianfei, Stagno, Jason R., Varticovski, Lyuba, Nimako, Eric, Rishi, Vikas, McKinnon, Kathy, Akee, Rhone, Shoemaker, Robert H., Ji, Xinhua, Vinson, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477234/
https://ncbi.nlm.nih.gov/pubmed/22851716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.080820
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