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CpG methylation of half-CRE sequences creates C/EBPα binding sites that activate some tissue-specific genes
DNA methylation of the cytosine in the CpG dinucleotide is typically associated with gene silencing. Genomic analyses have identified low CpG promoters that are both methylated and transcriptionally active, but the mechanism underlying the activation of these methylated promoters remains unclear. He...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996703/ https://ncbi.nlm.nih.gov/pubmed/21059933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008688107 |
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