Loading...

CpG methylation of half-CRE sequences creates C/EBPα binding sites that activate some tissue-specific genes

DNA methylation of the cytosine in the CpG dinucleotide is typically associated with gene silencing. Genomic analyses have identified low CpG promoters that are both methylated and transcriptionally active, but the mechanism underlying the activation of these methylated promoters remains unclear. He...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Rishi, Vikas, Bhattacharya, Paramita, Chatterjee, Raghunath, Rozenberg, Julian, Zhao, Jianfei, Glass, Kimberly, Fitzgerald, Peter, Vinson, Charles
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996703/
https://ncbi.nlm.nih.gov/pubmed/21059933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008688107
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!