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α-Conotoxin PeIA[S9H,V10A,E14N] Potently and Selectively Blocks α6β2β3 versus α6β4 Nicotinic Acetylcholine Receptors

Nicotinic acetylcholine receptors (nAChRs) containing α6 and β2 subunits modulate dopamine release in the basal ganglia and are therapeutically relevant targets for treatment of neurological and psychiatric disorders including Parkinson's disease and nicotine dependence. However, the expression...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hone, Arik J., Scadden, Mick'l, Gajewiak, Joanna, Christensen, Sean, Lindstrom, Jon, McIntosh, J. Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477225/
https://ncbi.nlm.nih.gov/pubmed/22914547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.080853
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