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α-Conotoxin PeIA[S9H,V10A,E14N] Potently and Selectively Blocks α6β2β3 versus α6β4 Nicotinic Acetylcholine Receptors

Nicotinic acetylcholine receptors (nAChRs) containing α6 and β2 subunits modulate dopamine release in the basal ganglia and are therapeutically relevant targets for treatment of neurological and psychiatric disorders including Parkinson's disease and nicotine dependence. However, the expression...

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Detalhes bibliográficos
Main Authors: Hone, Arik J., Scadden, Mick'l, Gajewiak, Joanna, Christensen, Sean, Lindstrom, Jon, McIntosh, J. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477225/
https://ncbi.nlm.nih.gov/pubmed/22914547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.080853
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