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A New Radioligand Binding Assay to Measure the Concentration of Drugs in Rodent Brain Ex Vivo

We have developed a new radioligand binding assay method to measure the concentration of nonradiolabeled drugs in the brain ex vivo. This new method fuses the concepts of standard competition and saturation binding assays and uses a transformed version of the Cheng-Prusoff equation (Biochem Pharmaco...

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Detalhes bibliográficos
Main Authors: Hussmann, G. Patrick, Kellar, Kenneth J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477219/
https://ncbi.nlm.nih.gov/pubmed/22899751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.198069
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