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A New Radioligand Binding Assay to Measure the Concentration of Drugs in Rodent Brain Ex Vivo
We have developed a new radioligand binding assay method to measure the concentration of nonradiolabeled drugs in the brain ex vivo. This new method fuses the concepts of standard competition and saturation binding assays and uses a transformed version of the Cheng-Prusoff equation (Biochem Pharmaco...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477219/ https://ncbi.nlm.nih.gov/pubmed/22899751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.198069 |
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