Pharmacokinetics of Oral d-Serine in d-Amino Acid Oxidase Knockout Mice

d-Amino acid oxidase (DAAO) catalyzes the oxidative deamination of d-amino acids including d-serine, a full agonist at the glycine modulatory site of the N-methyl-d-aspartate (NMDA) receptor. To evaluate the significance of DAAO-mediated metabolism in the pharmacokinetics of oral d-serine, plasma d-...

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Detalhes bibliográficos
Main Authors: Rais, Rana, Thomas, Ajit G., Wozniak, Krystyna, Wu, Ying, Jaaro-Peled, Hanna, Sawa, Akira, Strick, Christine A., Engle, Sandra J., Brandon, Nicholas J., Rojas, Camilo, Slusher, Barbara S., Tsukamoto, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477206/
https://ncbi.nlm.nih.gov/pubmed/22837388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.046482
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