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Genetic Variation in the Murine Lifespan Response to Dietary Restriction: from Life Extension to Life Shortening

Chronic dietary restriction (DR) is considered among the most robust life-extending interventions, but several reports indicate that DR does not always extend and may even shorten lifespan in some genotypes. An unbiased genetic screen of the lifespan response to DR has been lacking. Here we measured...

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Detalhes bibliográficos
Main Authors: Liao, Chen-Yu, Rikke, Brad A., Johnson, Thomas E., Diaz, Vivian, Nelson, James F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476836/
https://ncbi.nlm.nih.gov/pubmed/19878144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2009.00533.x
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