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Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1–induced collective directional migration and angiogenic sprouting

Angiogenic sprouting requires that cell-cell contacts be maintained during migration of endothelial cells. Angiopoietin-1 (Ang-1) and vascular endothelial growth factor act oppositely on endothelial cell junctions. We found that Ang-1 promotes collective and directional migration and, in contrast to...

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Detalhes bibliográficos
Main Authors: Oubaha, Malika, Lin, Michelle I., Margaron, Yoran, Filion, Dominic, Price, Emily N., Zon, Leonard I., Côté, Jean-François, Gratton, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476545/
https://ncbi.nlm.nih.gov/pubmed/22936663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-419721
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