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Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2

Tumors have been thought to initiate as avascular aggregates of malignant cells that only later induce vascularization. Recently, this classic concept of tumor angiogenesis has been challenged by the suggestion that tumor cells grow by co-opting preexisting host vessels and thus initiate as well-vas...

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Hlavní autoři: Vajkoczy, Peter, Farhadi, Mohammad, Gaumann, Andreas, Heidenreich, Regina, Erber, Ralf, Wunder, Andreas, Tonn, Jörg C., Menger, Michael D., Breier, Georg
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC150910/
https://ncbi.nlm.nih.gov/pubmed/11901186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14105
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