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Drosha regulates hMSCs cell cycle progression through a miRNA independent mechanism

Recently we demonstrated that the miRNA regulates human Mesenchymal Stem Cells (hMSCs) differentiation. To determine the role of the miRNA pathway in hMSCs proliferation, Drosha and Dicer knockdown hMSCs were generated using a lentiviral based tetracycline inducible shRNA. hMSCs with reduced Drosha...

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Main Authors: Oskowitz, Adam Z, Penfornis, Patrice, Tucker, Alan, Prockop, Darwin J, Pochampally, Radhika
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476475/
https://ncbi.nlm.nih.gov/pubmed/21794839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2011.07.005
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