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Drosha regulates hMSCs cell cycle progression through a miRNA independent mechanism

Recently we demonstrated that the miRNA regulates human Mesenchymal Stem Cells (hMSCs) differentiation. To determine the role of the miRNA pathway in hMSCs proliferation, Drosha and Dicer knockdown hMSCs were generated using a lentiviral based tetracycline inducible shRNA. hMSCs with reduced Drosha...

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Detalhes bibliográficos
Main Authors: Oskowitz, Adam Z, Penfornis, Patrice, Tucker, Alan, Prockop, Darwin J, Pochampally, Radhika
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476475/
https://ncbi.nlm.nih.gov/pubmed/21794839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2011.07.005
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