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Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation
The NLRP3 inflammasome is a key component of the innate immune response to pathogenic infection and tissue damage. It is also involved in the pathogenesis of a number of human diseases, including gouty arthritis, silicosis, atherosclerosis, and type 2 diabetes. The assembly of the NLRP3 inflammasome...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3476327/ https://ncbi.nlm.nih.gov/pubmed/22948162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.407130 |
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