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Preferential Repair of DNA Double-strand Break at the Active Gene in Vivo
Previous studies have demonstrated transcription-coupled nucleotide/base excision repair. We report here for the first time that DNA double-strand break (DSB) repair is also coupled to transcription. We generated a yeast strain by introducing a homing (Ho) endonuclease cut site followed by a nucleot...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3476307/ https://ncbi.nlm.nih.gov/pubmed/22910905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.364661 |
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