Cargando...

ATF4-dependent Regulation of the JMJD3 Gene during Amino Acid Deprivation Can Be Rescued in Atf4-deficient Cells by Inhibition of Deacetylation

Following amino acid deprivation, the amino acid response (AAR) induces transcription from specific genes through a collection of signaling mechanisms, including the GCN2-eIF2-ATF4 pathway. The present report documents that the histone demethylase JMJD3 is an activating transcription factor 4 (ATF4)...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Shan, Jixiu, Fu, Lingchen, Balasubramanian, Mukundh N., Anthony, Tracy, Kilberg, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476305/
https://ncbi.nlm.nih.gov/pubmed/22955275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.399600
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!