Oral Immunization of Dogs with Purified Cholera Toxin, Crude Cholera Toxin, or B Subunit: Evidence for Synergistic Protection by Antitoxic and Antibacterial Mechanisms
The immunogenicity and safety of purified cholera toxin (CT), its B subunit, and a crude culture filtrate of toxigenic Vibrio cholerae (CrT) were compared in dogs immunized orally and challenged with virulent V. cholerae. CT and CrT caused marked protection in two- or three-dose regimens. Protection...
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| Published in: | Infect Immun |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1982
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347586/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6889574/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.37.2.687-694.1982 |
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