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Effect of Device Design on the In Vitro Performance and Comparability for Capsule-Based Dry Powder Inhalers

This study investigated the effect of modifying the design of the Cyclohaler on its aerosolization performance and comparability to the HandiHaler at multiple flow rates. The Cyclohaler and HandiHaler were designated as model test and reference unit-dose, capsule-based dry powder inhalers (DPIs), re...

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Main Authors: Shur, Jagdeep, Lee, Sau, Adams, Wallace, Lionberger, Robert, Tibbatts, James, Price, Robert
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475852/
https://ncbi.nlm.nih.gov/pubmed/22723022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9379-9
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