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An Investigation into the Effect of Fine Lactose Particles on the Fluidization Behaviour and Aerosolization Performance of Carrier-Based Dry Powder Inhaler Formulations

The effect of milled and micronized lactose fines on the fluidization and in vitro aerosolization properties of dry powder inhaler (DPI) formulations was investigated, and the suitability of static and dynamic methods for characterizing general powder flow properties of these blends was assessed. La...

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Detalhes bibliográficos
Main Authors: Kinnunen, Hanne, Hebbink, Gerald, Peters, Harry, Shur, Jagdeep, Price, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113622/
https://ncbi.nlm.nih.gov/pubmed/24756910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0119-6
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