In Vitro Considerations to Support Bioequivalence of Locally Acting Drugs in Dry Powder Inhalers for Lung Diseases

Dry powder inhalers (DPIs) are used to deliver locally acting drugs (e.g., bronchodilators and corticosteroids) for treatment of lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). Demonstrating bioequivalence (BE) for DPI products is challenging, primarily due to an incom...

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Main Authors: Lee, Sau Lawrence, Adams, Wallace P., Li, Bing V., Conner, Dale P., Chowdhury, Badrul A., Yu, Lawrence X.
格式: Artigo
語言:Inglês
出版: Springer US 2009
主題:
Regulatory Note
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758114/
https://ncbi.nlm.nih.gov/pubmed/19495991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9121-4
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