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Increasing peripheral insulin sensitivity by PTP1B deletion improves control of blood pressure in obesity

Obesity is a major risk factor for hypertension (HT). The co-presentation of HT and insulin resistance (IR) suggests a role for IR in blood pressure (BP) dysregulation. To test this hypothesis peripheral IR has been genetically subtracted in a model of obesity by crossing leptin receptor mutant mice...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: de Chantemèle, Eric J. Belin, Ali, Mohammed. Irfan, Mintz, James D., Rainey, William E., Tremblay, Michel L., Fulton, David J., Stepp, David W.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475734/
https://ncbi.nlm.nih.gov/pubmed/23045458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.196295
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