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Genetic Deletion of NADPH Oxidase 1 Rescues Microvascular Function in Mice with Metabolic Disease

RATIONALE: Early vascular changes in metabolic disease that precipitate the development of cardiovascular complications are largely driven by reactive oxygen species (ROS) accumulation, yet the extent to which excess ROS derive from specific Nox isoforms remains ill-defined. OBJECTIVE: Identify the...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Thompson, Jennifer A., Larion, Sebastian, Mintz, James D., Belin de Chantemèle, Eric J., Fulton, David J., Stepp, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729041/
https://ncbi.nlm.nih.gov/pubmed/28684629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.309965
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