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Increasing peripheral insulin sensitivity by PTP1B deletion improves control of blood pressure in obesity
Obesity is a major risk factor for hypertension (HT). The co-presentation of HT and insulin resistance (IR) suggests a role for IR in blood pressure (BP) dysregulation. To test this hypothesis peripheral IR has been genetically subtracted in a model of obesity by crossing leptin receptor mutant mice...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3475734/ https://ncbi.nlm.nih.gov/pubmed/23045458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.196295 |
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