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pncA Mutations in the Specimens from Extrapulmonary Tuberculosis
BACKGROUND: Pyrazinamide (PZA) is an effective antitubercular drug that becomes toxic to Mycobacterium tuberculosis when converted to pyrazinoic acid by pyrazinamidase (PZase), encoded by mycobacterial pncA. A strong association was noted between the loss of PZase activity and PZA resistance. The ca...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Academy of Tuberculosis and Respiratory Diseases
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3475457/ https://ncbi.nlm.nih.gov/pubmed/23101013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4046/trd.2012.72.6.475 |
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