pncA mutations in clinical Mycobacterium tuberculosis isolates from Korea

BACKGROUND: Pyrazinamide (PZA) is among the first-line drugs for the treatment of tuberculosis. In vitro, it kills semidormant mycobacteria only at low pH. The purpose of this study was to compare PZA resistance with pyrazinamidase (PZase) activity and the genotype to better understand the molecular...

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Detalhes bibliográficos
Main Authors: Park, Soon Kew, Lee, Jung Yoo, Chang, Chulhun Ludgerus, Lee, Min Ki, Son, Han Chul, Kim, Cheol Min, Jang, Hyun Jung, Park, Hee Kyung, Jeong, Seok Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2001
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC33507/
https://ncbi.nlm.nih.gov/pubmed/11429043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-1-4
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