Sapap3 Deletion Causes mGluR5-Dependent Silencing of AMPAR Synapses

Synaptic transmission mediated by AMPA-type glutamate receptors (AMPARs) is regulated by scaffold proteins in the postsynaptic density. SAP90/PSD-95-associated protein 3 (SAPAP3) is a scaffold protein that is highly expressed in striatal excitatory synapses. While loss of SAPAP3 is known to cause ob...

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Hlavní autoři: Wan, Yehong, Feng, Guoping, Calakos, Nicole
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2011
Témata:
Brief Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475185/
https://ncbi.nlm.nih.gov/pubmed/22090495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2533-11.2011
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