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Sapap3 Deletion Causes mGluR5-Dependent Silencing of AMPAR Synapses
Synaptic transmission mediated by AMPA-type glutamate receptors (AMPARs) is regulated by scaffold proteins in the postsynaptic density. SAP90/PSD-95-associated protein 3 (SAPAP3) is a scaffold protein that is highly expressed in striatal excitatory synapses. While loss of SAPAP3 is known to cause ob...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3475185/ https://ncbi.nlm.nih.gov/pubmed/22090495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2533-11.2011 |
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