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Inhibition of osteoclastogenesis by RNA interference targeting RANK

BACKGROUND: Osteoclasts and osteoblasts regulate bone resorption and formation to allow bone remodeling and homeostasis. The balance between bone resorption and formation is disturbed by abnormal recruitment of osteoclasts. Osteoclast differentiation is dependent on the receptor activator of nuclear...

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Bibliografski detalji
Glavni autori: Ma, Ruofan, Xu, Jie, Dong, Bin, Kauther, Max Daniel, Jäger, Marcus, Wedemeyer, Christian
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475138/
https://ncbi.nlm.nih.gov/pubmed/22913338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-13-154
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