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Inhibition of osteoclastogenesis by RNA interference targeting RANK

BACKGROUND: Osteoclasts and osteoblasts regulate bone resorption and formation to allow bone remodeling and homeostasis. The balance between bone resorption and formation is disturbed by abnormal recruitment of osteoclasts. Osteoclast differentiation is dependent on the receptor activator of nuclear...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ma, Ruofan, Xu, Jie, Dong, Bin, Kauther, Max Daniel, Jäger, Marcus, Wedemeyer, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475138/
https://ncbi.nlm.nih.gov/pubmed/22913338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-13-154
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