Nf1 RasGAP Inhibition of LIMK2 Mediates a New Cross-Talk between Ras and Rho Pathways

BACKGROUND: Ras GTPases mediate numerous biological processes through their ability to cycle between an inactive GDP-bound form and an active GTP-bound form. Guanine nucleotide exchange factors (GEFs) favor the formation of the active Ras-GTP, whereas GTPase activating proteins (GAPs) promote the fo...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Vallée, Béatrice, Doudeau, Michel, Godin, Fabienne, Gombault, Aurélie, Tchalikian, Aurélie, de Tauzia, Marie-Ludivine, Bénédetti, Hélène
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2012
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474823/
https://ncbi.nlm.nih.gov/pubmed/23082153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047283
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