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Persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status
Memory CD8+ T cells are characterized by more rapid and robust effector function upon infection compared with naïve T cells, but factors governing effector gene responsiveness are incompletely understood. We sought to understand transcriptional control of the effector genes Ifng, Gzmb and Prf1 in mu...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474546/ https://ncbi.nlm.nih.gov/pubmed/21278341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003741 |
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