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Persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status

Memory CD8+ T cells are characterized by more rapid and robust effector function upon infection compared with naïve T cells, but factors governing effector gene responsiveness are incompletely understood. We sought to understand transcriptional control of the effector genes Ifng, Gzmb and Prf1 in mu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zediak, Valerie P., Johnnidis, Jonathan B., Wherry, E. John, Berger, Shelley L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474546/
https://ncbi.nlm.nih.gov/pubmed/21278341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003741
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