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Deficiency of CD8(+) effector memory T cells is an early and persistent feature of multiple sclerosis
BACKGROUND: Patients with multiple sclerosis (MS) have a deficiency of circulating CD8(+) T cells, which might impair control of Epstein–Barr virus (EBV) and predispose to MS by allowing EBV-infected autoreactive B cells to accumulate in the central nervous system. Based on the expression of CD45RA...
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| Publicado no: | Mult Scler |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361480/ https://ncbi.nlm.nih.gov/pubmed/24842963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458514536252 |
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