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A Phase I Clinical Study of High-Dose Ketoconazole Plus Weekly Docetaxel in Metastatic Castration-Resistant Prostate Cancer
PURPOSE: High-dose ketoconazole and docetaxel have shown activity as single agents against castration-resistant prostate cancer (CRPC). The goal of this phase I study was to determine the maximum tolerated doses, side effects, and pharmacokinetic interaction of coadministered docetaxel and ketoconaz...
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| Hoofdauteurs: | , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474294/ https://ncbi.nlm.nih.gov/pubmed/20399458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2010.02.020 |
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