A pharmacogenetic study of docetaxel and thalidomide in patients with castration-resistant prostate cancer using the DMET genotyping platform

The anticancer agent docetaxel shows significant inter-individual variation in its pharmacokinetic and toxicity profile. Thalidomide is an active anticancer agent and also shows wide pharmacological variation. Past pharmacogenetic research has not explained this variation. Patients with prostate can...

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Veröffentlicht in:Pharmacogenomics J
Hauptverfasser: Deeken, JF, Cormier, T, Price, DK, Sissung, TM, Steinberg, SM, Tran, K, Liewehr, DJ, Dahut, WL, Miao, X, Figg, WD
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6631360/
https://ncbi.nlm.nih.gov/pubmed/20038957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2009.57
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