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Abnormal adenosine-induced immunosuppression and cAMP metabolism in T lymphocytes of patients with systemic lupus erythematosus
Normal human T lymphocytes incubated with adenosine (10 μM) for 30 min at 37°C show an increase in the percentage of cells expressing receptors for the Fc portion of IgG (RFc(γ)) and the OKT8 antigen, while the proportion of OKT4(+) cells decreases. These effects occur exclusively in a subset of T c...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1982
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347376/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6296838/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.23.7542 |
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